Date Posted: 08/23/2023
Faculty/Division: Temerty Faculty of Medicine
Department: Department of Molecular Genetics
Campus: St. George (Downtown Toronto)
The Department of Molecular Genetics in the Faculty of Medicine, University of Toronto invites applications for the position of Research Associate (Limited Term) to design and lead research projects in the area of microbiology, functional genomics, chemical genomics, and antimicrobial drug resistance. Specifically, the program will focus on the molecular mechanisms by which metabolic flexibility controls virulence traits in fungal pathogens.
Candidates require a Ph.D. and at least four years of postdoctoral experience with demonstrated academic and research expertise in the field of mycology, genetics, genomics, and molecular biology. The incumbent will design and lead research pertaining to several projects in the lab focused on functional genomics, chemical genomics, fungal pathogenesis, and antimicrobial drug resistance. Extensive experience working with pathogenic fungi, including Candida albicans and Candida auris, is critical as is demonstrated experience with large-scale genetic mutant screens and mutant construction. Candidates must have experience with C. albicans molecular biology and biochemistry, including chromatin immunoprecipitation, monitoring transcript levels, epitope tagging, protein purification and monitoring protein post-translational modification, purification of mitochondria, and assays of mitochondrial function. Experience leading interdisciplinary work is critical, as is experience collaborating with structural biologists, computational biologists, and chemists. Candidates must have experience preparing manuscripts for submission to peer review publications/journals and assisting with preparing research proposals to be submitted to granting agencies. Candidates must have experience presenting findings at meetings and conferences. Candidates must have experience designing, planning, and executing experiments and research. Strong organizational, interpersonal, and communication skills are required, and candidates must be able to work positively with others and mentor trainees in a large collaborative laboratory.
Designing, planning, and executing research projects.
Designing and constructing mutants for functional genomic collections.
Performing assays that include but are not limited to: cloning, PCR, qRT-PCR, electrophoretic analysis, protein and enzyme assays, microbial transformations, drug resistance testing, screening mutant libraries, and functional and chemical genomic assays involving genome and barcode sequencing analysis.
Reading published papers relevant to the experiments being performed and adapting procedures accordingly.
Liaising with collaborators and assisting in the compilation, analysis and reporting of research findings to researchers within and outside of the program.
Preparing manuscripts for submission to peer review publications/journals.
Preparing research proposals to be submitted to granting agencies.
Beyond these responsibilities, the individual may be expected to participate in research supervision of two or more students or other trainees. At all times, the individual is expected to support the overall research and training missions of the lab.
This is a two (2) year term position.
All qualified candidates are encouraged to apply; however, Canadians and permanent residents will be given priority.
Closing Date: 12/31/2023,11:59PM ET
Employee Group: Research Associate
Appointment Type: Grant - Term
Pay Scale Group & Hiring Zone: R01 - Research Associates (Limited Term): $51,543 - $96,643
Job Category: Research Administration & Teaching