Help bring research to life and drive your career forward with the National Research Council of Canada (NRC), Canada's largest research and technology organization.
We are looking for a Research Officer (RO) with a strong expertise in T cell Immunology to support our Immunobiology Department in the Human Health Therapeutics (HHT) Research Center. The candidate would be someone who shares our core values of Integrity, Excellence, Respect and Creativity.
The Human Health Therapeutics Research Center provides innovative technologies and expertise to Canadian industry, academia and government through R&D services and collaborations, enabling them to develop new treatments to prevent or treat diseases cost effectively. As an R&D partner of choice, NRC HHT de-risks critical steps in the development of vaccines, biotherapeutics, and delivery of large molecules to emerging infections, cancers and chronic diseases. NRC HHT adds value to partners' products by overcoming challenges in target selection, candidate design, lead optimization, functional and biophysical characterization, immunogenicity and preclinical efficacy evaluation, and bioprocessing.
Applicants must demonstrate within the content of their application that they meet the following screening criteria in order to be given further consideration as candidates:
PhD in Immunology, Molecular Immunology or relevant area.
For information on certificates and diplomas issued abroad, please see Degree equivalency
Significant research experience in studying T-cell signalling pathways related to effector function, cell survival, maturation, differentiation, persistence, exhaustion, and immune tolerance.
Significant experience with molecular biology and immunological assays, including experience with cell culture, cell processing, flow cytometry, and cell-based functional assays and ability to utilize such tools and approaches for mechanism-of-action studies
Experience in immune cell biology relating to human autoimmune disease and/or cancer.
Significant experience in engineered cell therapy platforms including, but not exclusive to Chimeric Antigen Receptor (CAR) T cell therapies.
Demonstrated scientific leadership and research project management experience in the full spectrum of research activities as evident by peer-reviewed publication, competitive funding and research outreach;
Experience in leading a multidiscipline team or collaborative project, business development, marketing activities, and/or the development of partnerships and collaborations will be an asset.
Condition of Employment
Information on language requirements and self-assessment tests
Candidates will be assessed on the basis of the following criteria:
Superior knowledge of T cell Immunology, with emphasis on tolerance and T cell differentiation.
Advanced knowledge of modern techniques for monitoring inflammatory responses, immunogenicity, and biomarkers.
Knowledge of different pproaches to studying cellular signalling pathways and metabolism.
Knowledge of immunotherapies to combat chronic infection, autoimmune disease & cancer
Knowledge of genome editing approaches to modify safety, transplantation, persistence, efficacy of immune cell therapeutic products
Research - Communication (Level 2)
Research - Initiative (Level 2)
Research - Results orientation (Level 2)
Research - Teamwork (Level 2)
For this position, the NRC will evaluate candidates using the following competency profile(s): Research
Relocation assistance will be determined in accordance with the NRC's directives.
This position is classified as a Research Council Officer (RCO), a group that is unique to the NRC. The RCO group uses a person-based classification system instead of the more common duties-based classification system. Candidates are remunerated based on their expertise, skill, outcomes and impacts of their previous work experience. The salary scale for this group is vast, from $55,541 to $157,009 per annum, which permits for employees of all levels from new graduates to world renowned experts to be fairly compensated for their contributions.
A pre-qualified list may be established for similar positions for a one year period.
This position is being advertised internally and externally simultaneously, however first consideration will be given to internal NRC applicants.
NRC employees enjoy a wide-range of benefits including comprehensive health and dental plans, pension and insurance plans, vacation and other leave entitlements.
Preference will be given to Canadian Citizens and Permanent Residents of Canada. Please include citizenship information in your application.
The incumbent must adhere to safe workplace practices at all times.
We thank all those who apply, however only those selected for further consideration will be contacted.
Please direct your questions, with the requisition number (10074) to:
Closing Date: 10 July 2020 - 23:59 Eastern Time