Job Posting #901069
Position: Annotation/Curation Analyst
Site: Princess Margaret Cancer Center
Department: ADVANCED MOLECULAR DIAGNOSTICS LAB (AMDL)
Reports to: Director, Advanced Molecular Diagnostics Laboratory
Salary Range: $31.88 to $39.84 per hour commensurate with experience and consistent with UHN Compensation Policy
Hours: 37.5 HOURS PER WEEK
Status: TEMPORARY FULL-TIME (1 YEAR CONTRACT)
The Advanced Molecular Diagnostics Laboratory (AMDL) at the Princess Margaret Cancer Center is hiring an ANNOTATION/CURATION ANALYST. AMDL is a unique translational laboratory with the goal of developing and bringing to clinical molecular diagnostic use new genomic technologies for improved cancer care.
As an integral member of the Advanced Molecular Diagnostics Laboratory’s Variant Interpretation Group, the responsibilities of the Annotation/Curation Analyst include: utilizing software tools, databases and primary literature to investigate the clinical relevance of variants detected by genetic testing methods including next-generation sequencing (NGS); drafting concise variant interpretations; utilizing practical and theoretical knowledge for the analysis of NGS and other laboratory data, including somatic and germline testing; and completing required laboratory database and reporting activities related to variant analyses.
Other duties include completing assigned workload in a manner to ensure the efficient operation of the laboratory; participating in molecular profiling test development activities with laboratory technologists; maintaining quality control standards in assigned area; participating in communication activities to maintain and continually enhance the co-operation and coordination of services with other laboratory staff and with external lab clients; participating in professional development, teaching/education activities, safety and quality improvement programs to ensure excellence in the provision of services; adhering to Hospital and departmental mission and value statements while maintaining patient confidentiality; performing cross-functional duties as assigned, or requested; performing other duties related to and consistent with the job classification, as required.
Master’s degree in Molecular Genetics or related discipline required at minimum
One year minimum of relevant experience
Knowledge of and experience with molecular genetic variant assessment techniques
Knowledge of and experience with the use of genetic databases/resources and software (e.g. HGMD, COSMIC, gnomAD, cBioPortal, CIViC, ClinVar)
Knowledge of and experience with the theory and application of NGS platforms, and NGS analysis
Knowledge of the theory and practice of current NGS laboratory procedures, instruments, equipment and special techniques
Excellent problem recognition and problem-solving skills
Effective organizational, time management and prioritization skills
Excellent verbal and written communication skills
Ability to learn quickly, take in and distill large amounts of information and apply scientific knowledge
Scientific curiosity and interest to stay on top of emerging scientific data and trends
Demonstrated ability to take initiative, multitask and think critically
Ability to work independently and with cross-functional team members
Vaccines (COVID-19 and others) are a requirement of the job unless you have an exemption on a medical ground pursuant to the Ontario Human Rights Code.
Posting Date: June 23, 2022 Closing Date: Until Filled
For current UHN employees, only those who have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, and possess all the required experience and qualifications should apply.
UHN thanks all applicants, however, only those selected for an interview will be contacted.
UHN is a respectful, caring, and inclusive workplace. We are committed to championing accessibility, diversity and equal opportunity and welcomes all applicants including but not limited to: all religions and ethnicities, LGBTQ2s+, BIPOC, persons with disabilities and all others who may contribute to the further diversification of ideas. Requests for accommodation can be made at any stage of the recruitment process providing the applicant has met the Bona-fide requirements for the open position. Applicants need to make their requirements known when contacted.