Research Associate, Stem Cell Biology
BlueRock Therapeutics
Toronto, ON
  • Multiple Positions and Levels
BlueRock Therapeutics is a next-generation regenerative medicine company focused on breakthrough treatments and new horizons in medicine. BlueRock Therapeutics’ platform is based on state-of-the-art pluripotent stem cell engineering tools and expansion technology. The company represents a strategic partnership between Bayer and Versant Ventures, and has been granted access to one of the largest-ever Series A financings in biotech.

Our vision at BlueRock is to cure cardiovascular, neurologic and other diseases with significant unmet need and diminished self-repair potential. Our platform is enabled by strategic partnerships with leading academic and industry collaborators in the U.S., Canada and Japan.

BlueRock`s ambition is to have an R&D team of dynamic and highly engaged top scientists who are inspired to take project ownership and further develop themselves in one of the most rapidly growing scientific fields. At BlueRock we value open communication, collaboration and a positive and fun working environment in which both individual and team contributions are recognized. Our world-class management team is committed to fostering the growth and career development of employees.

The Toronto, Canada site is seeking to fill multiple Research Associate (Stem Cell Biology) positions in the Process Development team. The incumbent will be a key laboratory member in a dynamic and progressive team pioneering scaled manufacturing processes for the generation of therapeutic cells from pluripotent stem cells. Hands on experience with mammalian cell culture and corresponding analytical techniques are essential. Preferably, you have experience with pluripotent stem cell culture and differentiation, and/or primary cell culture. Familiarity with bioreactor technologies, cell culture process development, and cGMP manufacturing requirements are a plus.

This is an outstanding opportunity to contribute to bringing a new class of cell-based medicines to patients. Collaboration with a highly-motivated, world-class team of scientists and engineers promises an exciting and engaging work environment for motivated, self-starting candidates.

Position Description:
Participate in design and execution in vitro experiments to develop and characterise scalable processes for cultivation of pluripotent stem cells and derivatives.
Identify and determine appropriate ranges for (critical) process parameters for cell culture and downstream processing to optimize product yield and quality.
Develop and optimize processes and systems to scale production of PSCs and derivatives in a cGMP compliant manner.
Analyze and document experimental data in electronic laboratory notebooks in a timely and accurate manner in accordance with the company quality management system.
Prepare and follow standard operating procedures, batch records and other process documentation.
Present scientific data to colleagues at internal meetings.

Minimum Requirements:
MSc. In biological sciences, biological engineering, or similar.
Extensive mammalian cell culture and cell characterisation experience. Preferably, human pluripotent stem cell culture and differentiation, and/or primary cell culture experience.
Experience with, and functional understanding of cell characterisation methods and technologies (e.g., flow cytometery, qPCR, immunoassays, microscopy).
Demonstrated ability to plan experiments and independently execute complex tasks.
Excellent data recording and analysis skills, including statistical treatment of data.
Strong English written and verbal communications skills.