Senior Bioinformatics Analyst
University Health Network
Toronto, ON
University Health Network (UHN) is looking for an experienced professional to fill the key role of Senior Bioinformatics Analyst in our Research Department.

Transforming lives and communities through excellence in care, discovery and learning.

The University Health Network, where “above all else the needs of patients come first”, encompasses Toronto Rehabilitation Institute, Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre and the Michener Institute of Education at UHN. The breadth of research, the complexity of the cases treated, and the magnitude of its educational enterprise has made UHN a national and international resource for patient care, research and education. With a long tradition of groundbreaking firsts and a purpose of “Transforming lives and communities through excellence in care, discovery and learning”, the University Health Network (UHN), Canada’s largest research teaching hospital, brings together over 16,000 employees, more than 1,200 physicians, 8,000+ students, and many volunteers. UHN is a caring, creative place where amazing people are amazing the world.

University Health Network (UHN) is a research hospital affiliated with the University of Toronto and a member of the Toronto Academic Health Science Network. The scope of research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. Research across UHN's five research institutes spans the full spectrum of diseases and disciplines, including cancer, cardiovascular sciences, transplantation, neural and sensory sciences, musculoskeletal health, rehabilitation sciences, and community and population health. Find out about our purpose, values and principles here.

A full-time position is available at the Princess Margaret Cancer Centre in Toronto, Canada. The successful candidate will work to support the bioinformatics efforts and to help organize, plan, analyze, and interpret the results from a variety of exciting projects that are currently ongoing and planned. The successful candidate will work on existing and future RNA-seq, whole genome sequencing, chromatin conformation capture, CyTOF and single-cell RNA-sequencing data sets generated from a variety of cellular and murine model systems.

The successful candidate will have all the tools required to accomplish their goals, including dedicated access to the hospital’s high-performance computing infrastructure, which is one of the top systems in Canada devoted to health care research. In addition to this, you will work with collaborating bioinformaticians at the Princess Margaret Bioinformatics and Computing Core, and with researchers abroad (Catalan institute of Oncology, IDIBELL, Barcelona).

Qualifications:
Candidates must have a Bachelor's degree or higher in computer science, bioinformatics and biostatistics/statistics or a recognized equivalent, Master's degree is preferred
Minimum 4 years of relevant experience with a Masters degree or 6 years of relevant experience with a Bacherlors degree
Hands-on experience in the use of Unix/Linux, R/Matlab, and statistical approaches (including Machine Learning techniques) to analyze and visualize genome-scale data sets.
Preferred but not required are expertise in a scripting language (Python, Perl), best practices for software development (version control, etc.) and the use of high-performance computing systems (eg. TORQUE) for analyzing large data sets.
Hands-on experience processing and analyzing next-generation sequencing data, ATAC-seq and RNA-Sequencing data analysis is preferred.
Experience with single cell sequencing data (Fluidigm C1, 10X, Dropseq etc.) and tools (Seurat, SCONE, SINGuLAR etc.) is a strong plus.
Ideally, the successful candidate will have some familiarity with the basic principles of immunology, DNA damage responses, genetics and cancer biology.
Candidates should have a strong sense of teamwork, be highly motivated, possess excellent organizational, problem-solving and communication skills (both verbal and written)
Preferred if the candidate has relevant publications in any of the fields of: immunology, cancer, genomics, statistics, or computational algorithms or tools
An exciting and fast paced place to work, we are looking for that ideal mixture of technical skills, biology, and creativity to grow and sustain bioinformatics efforts. Excellent salary and benefits will be provided.

If you are interested in making your contribution at UHN, please apply on-line. You will be asked to copy and paste as well as attach your resume and covering letter. You will also be required to complete some initial screening questions.

POSTED DATE: October 31, 2019 CLOSING DATE: Until filled

For current UHN employees, only those who have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, and possess all the required experience and qualifications should apply.

University Health Network thanks all applicants, however, only those selected for an interview will be contacted.

UHN is a respectful, caring, and inclusive workplace. We are committed to championing accessibility, diversity and equal opportunity. Requests for accommodation can be made at any stage of the recruitment process providing the applicant has met the Bona-fide requirements for the open position. Applicants need to make their requirements known when contacted.