The candidate will develop dosage formulation (delivery system) of antimicrobial peptides (AMPs) to be administered intravaginally. We will focus on the cathelicidin AMP, LL-37, and its derived peptide, 17BIPHE2, which possess both spermicidal and microbicidal activity (Kiattiburut et al., Human Reprod 2018, 33:2175-2183). As Multipurpose Prevention Technology (MPT) agents, these AMPs will provide women with empowerment to protect themselves against unwanted pregnancies and sexually transmitted infections. This study is funded by Canadian Institutes of Health Research (CIHR) and is being carried out in both mouse (in vitro and in vivo) and human (in vitro and ex vivo) systems. There is a sizable group of researchers in OHRI, who perform research on reproductive biology with collaborations with researchers in other institutes in Ottawa and worldwide.
Basic Requirements:
- Postdoctoral candidates should hold a PhD in Cell Biology/Physiology, and Biochemistry (or related biomedical fields)
- Flexible and cooperative spirit with strong commitment to team efforts
- Excellent critical thinking and analytical skills
- Excellent communication and writing skills
- Demonstrated passion for innovative research
Preferred Qualification:
- Knowledge and lab experience in the female reproductive physiology, sperm biology, and hydrogel and/or nanoparticles-based drug delivery to the vagina will give priorities
- Self -motivation to progress in his/her career as an independent investigator will also be favorably considered.
Contract Details:
The full-time contract is for one year and is renewable with an excellent benefits package
Salary: Minimum annual stipend – years since obtained doctoral degree –
PDF 0-2 years; $44,000 ($22.564/hr.)
PDF 3-7 years; $46,000 ($23.590/hr.)
Comments to Applicant:
Please send a complete CV with description of research experience to:
Contact Info:
Name: Dr. Nongnuj Tanphaichitr
Title: Senior Scientist PhD
Program: Chronic Disease Program
Ottawa Hospital Research Institute
Address: 501 Smyth Road CCW 3rd Floor
Email: ntanphaichitr@ohri.ca
Website: http://www.ohri.ca/profiles/tanpha.asp
We thank all applicants for their interest. However, only those invited for an interview will be contacted. The Ottawa Hospital Research Institute is an equal opportunity employer. Upon request, accommodations due to a disability are available throughout the selection process.