Faculty of Medicine & Dentistry - Oncology Department
Competition No. - A105343194
Closing Date - Will remain open until filled.
The postdoctoral researcher will be joining an international team of scientists and partners that are rapidly developing, validating, manufacturing and deploying a medical countermeasure to protect the majority of the Canadian population from SARS-CoV-2 infection and COVID-19 disease. This countermeasure, is a DNA-vaccine encoding highly optimized epitopes to induce neutralizing antibodies against SARS-COV-2 spike protein to block viral entry. Incorporation of epitopes from multiple conserved viral proteins should provide durable immunity against existing and future emergent coronaviruses.
The postdoctoral researcher should be able to provide advanced molecular, cellular, pharmacological and physiological expertise to help advance the COVID-19 DNA-vaccine program. The role requires skills in experimental design and data analysis as well as an ability to provide results in a form easily understood by academic and sometimes pharmaceutical industry groups. The successful candidate will incorporate results into user-friendly presentations that support decision making by the principal investigator and potential pharmaceutical industry partners. Specifically, the incumbent will be responsible for conducting laboratory experiments to support the DNA-based COVID-19 vaccine development. The duties will include the execution of various molecular biology techniques such as, cell culture, DNA extraction, microflow cytometry and lipid nanoparticle encapsulation.
Planning research activities and providing research design for a project and/or program
Determining the most appropriate methodology in carrying out identified research goals
Designing experiments, data collection protocols, and standards
Conducting advanced analysis of research results
Overseeing and/or conducting data collection activities
Preparing proposals for new research activities, including assisting in the preparation of research grant applications and contract proposals
Participating in the writing of research papers, the preparation of presentations and publications
Presenting research results in laboratory meetings, seminars, scientific conferences and/or related settings
Training and supervising new support staff, students and post-doctoral fellows
Ensuring conformity to biosafety and radiation safety regulations
Ordering and maintaining lab equipment and supplies
Fostering communication with off-campus partners
Assisting with related administrative duties as required by the principal investigator
Knowledge, Skills and Abilities
Ph.D. in Cell Biology, Biochemistry, Pharmacology, Immunology or Oncology (Immunology preferred)
Experience in Cell Biology, Biochemistry, Pharmacology, or Immunology (Immunology preferred) encompassing broad molecular and cellular research
Proven accomplishments in Cell Biology, Biochemistry, Pharmacology, or Immunology (Immunology preferred) with an emphasis on virology and extracellular vesicle biology
Wide experience in isolation and culturing of cells from primary human cells from multiple tissues and extensive expertise in the growth and transfection/transduction of various types of cell lines is also required.
Ability to work independently as well as contributing to team development, including during the supervisor's periodic absences from the lab is a must.
We thank all applicants for their interest; however, only those individuals selected for an interview will be contacted.
Salary will commensurate with experience and qualifications.
How to Apply
All qualified candidates are encouraged to apply; however, Canadians and permanent residents will be given priority. If suitable Canadian citizens or permanent residents cannot be found, other individuals will be considered. The University of Alberta is committed to an equitable, diverse, and inclusive workforce. We welcome applications from all qualified persons. We encourage women; First Nations, Métis and Inuit persons; members of visible minority groups; persons with disabilities; persons of any sexual orientation or gender identity and expression; and all those who may contribute to the further diversification of ideas and the University to apply.