Forest machine Jobs

Real World Biostatistician - RWE CMH experience (hiring in Canada and US)
Syneos - Clinical and Corporate - Prod —Remote
- Full-time
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Real World Biostatistician - RWE CMH experience (hiring in Canada and US)

Syneos - Clinical and Corporate - Prod
Remote

Apply Now

Job details

Full-time

Skills

Microsoft Powerpoint
Statistics
Doctoral degree
Electronic medical records
SAS
Data structures
R
Responsive design
Master's degree
SQL
Machine learning
Communication skills
Python
Analytics

Full job description

Real World Biostatistician - RWE CMH experience (hiring in Canada and US)

Syneos Health® is a leading fully-integrated life sciences services organization built to accelerate customer success. We partner with innovators at every point across the drug development and commercialization continuum, helping them navigate complexity, anticipate change and accelerate progress.

Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape.

Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to deliver – for one another, our customers, and, most importantly, for those in need.

Discover what your 25,000 future colleagues already know:

Why Syneos Health

We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
We are committed to building an inclusive culture – where you can authentically be yourself. Central to this is our purpose – Driven to Deliver – which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone’s life.
We are continuously building the company we all want to work for and our customers want to work with. Why? Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress.

Job Responsibilities

Job Description

Biostatistician – Real-World Evidence (RWE)

Role Overview

We are seeking a biostatistician with strong experience in real-world data (RWD) with observational study design and safety study experience in addition to RWE CMH experience. This role will support evidence generation across multiple therapeutic areas. This role will focus on the design, analysis, and interpretation of observational studies using EMR and claims data to inform: clinical development, HEOR, regulatory strategy, and market access.

Key Responsibilities

Design and execute real-world evidence (RWE) studies using EMR and claims data; Conducting data specs, SAP and protocol with key research objectives

Develop and apply robust statistical methodologies, including:

Causal inference methods (e.g., propensity score methods, weighting, matching; GLM or GLMM, MMRM; survival analysis; random forest)

Trial emulation frameworks

External control arm development and borrowing strategies

Perform data analysis using healthcare coding systems (e.g., ICD, NDC)

Conduct sample size estimation and power calculations for observational and hybrid study designs

Collaborate cross-functionally with stakeholders across:

HEOR

Market Access

Regulatory

Clinical Development

Translate complex analytical results into clear, actionable insights, e.g. powerpoint or study report for decision-making

Support methodological innovation in RWE, including integration of machine learning approaches where appropriate

Required Qualifications

M.S. or Ph.D. in Biostatistics, Statistics, Epidemiology, or related field

- 5 years of experience in RWD/RWE analytics (industry or equivalent)

Strong experience with EMR and/or claims data

Proficiency in healthcare coding systems (e.g., ICD, NDC)

Programming expertise in at least one of: SAS, R, or Python

Working knowledge with SQL logic and OMOP data structures

Solid understanding of:

Causal inference methods

Observational study design

Sample size and power considerations

Some examples: Independently write cohort definitions in SQL logic; Debug data issues e.g., time zero alignment, exposure gaps; Understand concept mapping (ICD SNOMED RxNorm); Translate statistical estimand censoring rule and data extraction logic
RWE CMH Experience

Preferred Qualifications

Ph.D. strongly preferred

Experience in one or more therapeutic areas:

Diabetes

Cardiovascular disease

Metabolic disorders

Familiarity with:

Trial emulation methodologies

External control borrowing / hybrid designs

Basic machine learning methods applied to RWD

Demonstrated ability to work across multiple therapeutic areas (TAs) in a fast-paced environment

Strong communication and stakeholder engagement skills

Advanced (nice-to-have, not always required)

Build reusable cohort pipelines

Optimize queries for large-scale databases

Work across multiple CDMs (OMOP, Sentinel, PCORnet)

Core Competencies

Analytical rigor and methodological depth

Cross-functional collaboration

Ability to operate with agility across diverse projects and therapeutic areas

Clear and effective scientific communication

Get to know Syneos Health

Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.

No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.

http://www.syneoshealth.com

Additional Information

Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.

Apply Now

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Real World Biostatistician - RWE CMH experience (hiring in Canada and US)

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